N.F.L. Picks: Steelers Over Lions; Cowboys Over Redskins

Detroit’s defense is not nearly as crisp as Pittsburgh’s, but it can be just as opportunistic. If Roethlisberger is at all careless with his passes, Detroit will make him pay for it. Golden Tate’s being limited, or possibly inactive, with a sprained AC joint takes some jolt out of the Lions’ offense, but this should be a close game. Pick: Steelers

49ers at Eagles, 1 p.m., Fox

Line: Eagles by 13

The 49ers (0-7) are very bad. The Eagles (6-1) are very good. It is not hard to predict that Philadelphia will take care of business at home against a winless opponent, but a spread of 13 points is demanding a blowout, and San Francisco’s plucky young defense may be up to the task of preventing that from happening. As good as the Eagles have been, they have kept things close in four of their six wins, and they have little reason to try to run up the score against an overmatched opponent. Pick: 49ers

Texans at Seahawks, 4:05 p.m., CBS

Line: Seahawks by 5.5

Thanks to the emergence of Deshaun Watson, the Texans (3-3) have averaged 39.3 points a game over the last four weeks. The hype has been deafening, but in reality, he has yet to face a very challenging defense. That ends…

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